Findings from a prospective, randomized clinical studyInnovative approaches to combination therapy in type 1...
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Illuminating Personalized Medicine
Illuminating Personalized Medicine
Porphyrin-based Aggregation-induced Emission Generating Molecules for Continuous Multi-Metabolite Monitoring
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Personialized Medicine Study
In this project, a new sensor technology is being developed to improve the monitoring of multiple metabolites. Special molecules with aggregation-induced emission, known as AIEgens, are utilized, which emit particularly bright luminescence upon aggregation. These AIEgens are designed to emit light in different spectral regions, enabling the simultaneous measurement of various metabolites such as glucose, lactate, and ketones. Integrated into a biocompatible matrix and applied to the tip of an optical sensor, which is incorporated into a wearable device, this minimally invasive system allows for continuous monitoring of metabolism in the interstitial fluid under the skin. This technology has the potential to significantly improve diagnosis and personalized treatment for conditions like diabetes and cardiovascular diseases.
Project team: Prof. Lilian Witthauer, Dr. Emmanouil Rousakis
Funding: Swiss National Science Foundation
More recent projects
AID-JUNCT study: GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery
Obesogenic microbiota Project
Exploring the connection: obesity, gut microbiome, and metabolic healthCause and effect relationship between obesity...
Bacterial metabolites modulating Immune Function
Exploring microbial metabolites and immune activationUnveiling the role of bacterial metabolites in dendritic cell...
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