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Menstrual Cycle Study: Identifying changes in insulin sensitivity across the menstrual cycle in T1D

Menstrual Cycle Study: Identifying changes in insulin sensitivity across the menstrual cycle in T1D

Menstrual Cycle Study: Identifying changes in insulin sensitivity across the menstrual cycle in T1D

DCB and Tidepool are entering a partnership to explore the relationship between diabetes and women’s health. The first initiative in this collaboration focuses on the menstrual cycle’s influence on insulin-dependent diabetes.

Menstrual Cycle Study

Recognising the challenges faced by women with insulin-dependent diabetes, research specifically investigating the menstrual cycle’s impact on diabetes management remains limited so far. This lack of focused study has hindered the development of tailored treatment strategies for women.

Diabetes Center Berne (DCB) and Tidepool aim to fill this critical research gap. The joint effort is focused on examining the interplay between the menstrual cycle and diabetes management, with the goal of enhancing care and improving quality of life.

With the goal of supporting the development of clinical guidance, tools, and products to reduce the burden of diabetes management throughout the menstrual cycle, Tidepool and DCB are joining forces to explore the relationship between menstrual cycles and insulin-dependent diabetes. While Tidepool facilitates access to the data of people living with type 1 diabetes who menstruate and provides their expertise in data collection for this initiative, DCB provides expertise in clinical research and research infrastructure.

Project team: Dr. Martina Rothenbühler (Project Leader Data Sciences, DCB), Stefanie Hossmann (Clinical Research Scientist, DCB), Maya Friedman (Founder of the Tidepool Period Project, Tidepool), Saira Khan-Gallo (Access & Equity Lead, Tidepool)

Project partner: Tidepool

 

About the Study Partners

DCB supports ideas and projects in the field of diabetes technology worldwide by providing expertise, access to clinical research facilities and its own laboratories, as well as financial resources. The goal is to bring them a big step closer to market entry in a collaborative partnership. The work of the DCB is non-profit –  the goals are new insights and innovations around diabetes management as well as a vibrant community. 

Tidepool is a 501(c)(3) nonprofit organization. It was founded by people with diabetes, caregivers, and leading healthcare providers committed to helping all people with insulin-requiring diabetes safely achieve great outcomes through more accessible, actionable, and meaningful diabetes data.

Study requirements for U.S. residents

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Menstrual Cycle Study Team

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enhance-d: Enhanced Diabetes Self-Management

enhance-d: Enhanced Diabetes Self-Management

enhance-d: Enhanced Diabetes Self-Management

Diabetes technology generates a lot of data, but rarely is all this data used to inform action. DCB supports enhance-d in combining real-time diagnostics across every aspect of the digital diabetes experience with AI-powered analytics and visualisations to see, diagnose and explain glucose self-management.

Making Sense of Diabetes Data to Inform Self-Management

Diabetes management is influenced by many different factors at all times, including nutrition and exercise. Advances in technology are making data capture of all factors easier than ever before – but how can people with diabetes inform their actions based on this huge amount of data?

enhance-d combines real-time diagnostics across every aspect of the digital diabetes experience with AI-powered analytics and user-friendly visualisations to see, diagnose and explain glucose management. Based on the team’s previous experience working with professional athletes with diabetes, they are familiar with the challenge of creating optimal training plans considering all influencing factors. With enhance-d, their goal was to develop a solution that could generate a simplified overview for everyone, whether professional athletes or individuals simply starting regular exercise.

enhance-d stands for improved self-management for people with diabetes using a simple digital solution. CGM and other portable data allows an understanding of how pharmacologic, behavioural, dietary and activity-based interventions contribute to changes in glucose profiles – and how users can take action based on these findings.

Project Team: Federico Fontana (Founder & CEO), Sam Scott (Founder & CSO), Fabio Saviozzi (Founder & CCO), Felipe Mattioni Maturana (Founder & CTO).

Project support: DCB supports enhance-d financially with 150’000 CHF as well as with access to our network of experts and our knowledge in product development.

enhance-d founders Fabio Saviozzi, Sam Scott, Federico Fontana and Felipe Mattioni Maturana

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SmartStart Health: Unlocking life​-​changing benefits of CGM in diabetes

SmartStart Health: Unlocking life​-​changing benefits of CGM in diabetes

SmartStart Health: Unlocking life​-​changing benefits of CGM in diabetes

DCB and SmartStart Health collaborate to develop and validate a world-first patient education mobile app to increase knowledge and improve outcomes among people with diabetes using continuous glucose monitoring (CGM).

Overwhelming amount of CGM data

When people with diabetes/caregivers start using CGM to gain tighter diabetes control, they face a steep learning curve, regardless of how many years they have lived with diabetes. They’re overwhelmed by hundreds of data points per day, trend arrows and fine-tuning settings for alerts and alarms. They are aware that CGM can be a powerful tool for minimising high and low blood glucose levels and improving their quality of life, but they aren’t sure how to achieve these outcomes. Without timely support to use CGM effectively, people with diabetes/caregivers may see CGM data as clear documentation of diabetes management challenges they feel they cannot overcome.

SmartStart CGM as an innovative solution for CGM education

Education is important for people using CGM to be able to understand and use CGM data to make appropriate treatment decisions that lead to quality of life benefits as well as improvements in diabetes outcomes. SmartStart Health is rising to the challenge of CGM-specific patient education with SmartStart CGM, a user-friendly smartphone app. Supported by DCB, diabetes centres in the US and Switzerland will evaluate the new scalable solution in a proof-of-concept study. The partnership aims to analyse the results in Q3 2022 and publish by mid-2023.

The SmartStart CGM app is designed to inform and empower users with interactive micro-learning based on real-world scenarios that reflect the reality of living with diabetes. A telehealth portal for healthcare professionals will enable clinicians to assess patient engagement with the programme.

Project team: Melissa Holloway (Founder & CEO), Kieron Heath (Operations), Effra Digital (Technology consultant), Will Hargreaves (Business development), Jamie Welsh (Content development)

Funding: DCB supports SmartStart Health with 100k CHF funding

Melissa Holloway, CEO and Founder of SmartStart Health

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DCB Research AG

Freiburgstrasse 3
3010 Bern
Switzerland